Cincinnati is a city in the U.S. state of Ohio and the county seat of Hamilton County. The municipality is located north of the Ohio River at the Ohio-Kentucky border. The population within city limits was estimated to be 333,336 in 2008, making it the state's third largest city. According a 2008 Census Bureau estimate, the Cincinnati Metropolitan Area had a population of 2,155,137 making it the largest MSA in Ohio, and the 24th most populous in the United States. Residents of Cincinnati are called Cincinnatians.
Cincinnati is considered to have been the first American boomtown in the heart of the country in the early nineteenth century to rival the larger coastal cities in size and wealth. As the first major inland city in the country, it is sometimes thought of as the first purely American city, lacking the heavy European influence that was present on the east coast. However, by the end of the nineteenth century, Cincinnati's growth had slowed considerably, and the city was surpassed in population by many other inland cities.
Cincinnati is home to major sports teams including the Cincinnati Reds and the Cincinnati Bengals, as well as events like the Cincinnati Masters and the Thanksgiving Day race. The University of Cincinnati traces its foundation to the Medical College of Ohio, which was founded in 1819.